Pregnancy Loss Following Amniocentesis or CVS Sampling-Time for a Reassessment of Risk.
Pregnancy Loss Following Amniocentesis or CVS Sampling-Time for a Reassessment of Risk.
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DOI：
10.3390/jcm3030741
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发表时间：
2014-07-08
影响因子：
3.9
通讯作者：
Akolekar R
中科院分区：
文献类型：
--
作者：
Ogilvie C;Akolekar R
目前在英国广泛引用的与手术相关的妊娠丢失风险为1%的子宫穿刺术和1.5%的绒毛膜绒毛取样。已发表的数据表明，这些风险数据已经过时且不准确，需要为考前咨询制定新的指导方针。我们认为，在为妇女提供咨询时，有关流产风险的准确和循证信息至关重要，因为夸大这种风险可能会阻止妇女进行检测，或者在流产发生时引起不合理的悔恨。同样重要的是，卫生保健经济学家在应用风险效益分析评估非侵入性筛查新技术时，要了解“程序相关风险”的最新证据。
Risk of procedure-related pregnancy loss is currently widely quoted in the UK as 1% for amniocentesis and 1.5% for chorionic villus sampling. Published data suggest that these risk figures are out of date and inaccurate, and that new guidelines are required for pre-test counseling. It is our opinion that accurate and evidence-based information concerning miscarriage risk is vital when counseling women, as exaggeration of this risk may deter women from testing, or cause unjustified remorse if a miscarriage ensues. It is also essential that health-care economists are aware of the up-to-date evidence on “procedure-related risk” when applying risk-benefit analysis to assess new technology for non-invasive screening.