Visualizing ex vivo radiofrequency and microwave ablation zones using electrode vibration elastography
Visualizing ex vivo radiofrequency and microwave ablation zones using electrode vibration elastography
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DOI：
10.1118/1.4758061
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发表时间：
2012-11-01
期刊：
影响因子：
3.8
通讯作者：
Brace, Chris L.
中科院分区：
文献类型：
--
作者：
DeWall, Ryan J.;Varghese, Tomy;Brace, Chris L.
目的：电极振动弹性成像是一种新的剪切波成像技术，可用于显示热消融区。先前的工作已经表明，电极振动弹性成像描绘射频消融的能力，但是，还没有以前的研究描绘微波消融或放射病理学的相关性使用多个observers.Methods：Radiobservation和微波消融形成在离体牛肝组织。在剪切波速度和最大位移图像上比较了它们的可视化。将消融尺寸与大体病理学进行比较。弹性成像和大体病理重叠和观察者间的变异性进行了量化使用相似性measurements.Results：弹性成像与大体病理相关。射频消融的面积估计相关性优于微波消融，射频消融和微波消融的剪切波速度图像Pearson系数分别为0.79和0.54，最大位移图像Pearson系数分别为0.90和0.70。对于射频消融和微波消融，弹性成像和大体病理学之间面积的绝对相对差异在剪切波速度图像上分别为18.9%和22.9%，在最大位移图像上分别为16.0%和23.1%。在本研究中观察到具有统计学意义的放射学-病理学相关性，但相关系数低于其他模数成像技术，尤其是在微波消融中。观察员对大多数热消融提供了类似的描述。这些结果表明，电极振动弹性成像是能够成像热消融，但细化的技术可能是必要的，然后才能用于监测热消融手术的临床。(C)2012年美国医学物理学家协会。[http：//dx.doi.org/10.1118/1.4758061]
Purpose: Electrode vibration elastography is a new shear wave imaging technique that can be used to visualize thermal ablation zones. Prior work has shown the ability of electrode vibration elastography to delineate radiofrequency ablations; however, there has been no previous study of delineation of microwave ablations or radiological-pathological correlations using multiple observers.Methods: Radiofrequency and microwave ablations were formed in ex vivo bovine liver tissue. Their visualization was compared on shear wave velocity and maximum displacement images. Ablation dimensions were compared to gross pathology. Elastographic imaging and gross pathology overlap and interobserver variability were quantified using similarity measures.Results: Elastographic imaging correlated with gross pathology. Correlation of area estimates was better in radiofrequency than in microwave ablations, with Pearson coefficients of 0.79 and 0.54 on shear wave velocity images and 0.90 and 0.70 on maximum displacement images for radiofrequency and microwave ablations, respectively. The absolute relative difference in area between elastographic imaging and gross pathology was 18.9% and 22.9% on shear wave velocity images and 16.0% and 23.1% on maximum displacement images for radiofrequency and microwave ablations, respectively.Conclusions: Statistically significant radiological-pathological correlation was observed in this study, but correlation coefficients were lower than other modulus imaging techniques, most notably in microwave ablations. Observers provided similar delineations for most thermal ablations. These results suggest that electrode vibration elastography is capable of imaging thermal ablations, but refinement of the technique may be necessary before it can be used to monitor thermal ablation procedures clinically. (C) 2012 American Association of Physicists in Medicine. [http://dx.doi.org/10.1118/1.4758061]