The Differential Role of Vitamin D in Type 2 Diabetes Management and Control in Minority Populations.
The Differential Role of Vitamin D in Type 2 Diabetes Management and Control in Minority Populations.
复制标题
维生素 D 在少数民族人群 2 型糖尿病管理和控制中的不同作用。
DOI：
10.1007/s10903-019-00857-x
复制
发表时间：
2019
影响因子：
1.9
通讯作者：
Lee,Ju-Young
中科院分区：
文献类型：
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作者：
Kim,MiyongTo;Kim,KimByeng;Ko,Jisook;Murry,Nicole;Levine,David;Lee,Ju-Young
维生素D缺乏与2型糖尿病(T2 DM)的发病率以及T2 DM患者的血糖控制不良有关，但关于其在少数民族人群中的相关性的比较研究很少。利用韩裔美国人(KAS)对患有T2 DM(N= 250KAS)的行为干预研究的基线数据和NHANES数据集，我们探讨了维生素D在几个种族群体中对HbA1C水平或T2 DM控制的不同作用。更多的KA(55.2%)缺乏维生素D(美国平均水平为37.8%)。在少数人群中确定了维生素D缺乏的共同和独特的相关性，包括在非糖尿病和糖尿病人群中维生素D和HbA1C之间的显著关联。未来的研究有必要解释维生素D和血糖控制效果的因果机制，并检查某些少数群体中与维生素D缺乏相关的背景因素。临床试验注册：IDENTIFIER NCT01264796
Vitamin D deficiency is associated with incidence of type 2 diabetes (T2DM) as well as poor glycemic control among T2DM patients, yet comparative studies of its association among ethnic minority populations are scarce. Using baseline data from a behavioral intervention study of Korean Americans (KAs) with T2DM (N= 250 KAs) and the NHANES data set, we explored differential roles of vitamin D on HbA1Clevel or T2DM control in several racial groups. Significantly more KAs (55.2%) were vitamin D-deficient (U.S. average, 37.8%). Both common and unique correlates of vitamin D deficiency in minority populations were identified, including significant associations between Vitamin D and HbA1Cin both non-diabetic and diabetic populations. Future studies are warranted to explain the causal mechanism of the effect of vitamin D and glycemic control as well as to examine contextual factors associated with vitamin D deficiency in certain minority groups.Clinical Trials Registry: Identifier NCT01264796