Changes of ROS during a Two-day Ultra-marathon Race
Changes of ROS during a Two-day Ultra-marathon Race
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DOI：
10.1055/s-0028-1112144
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发表时间：
2009-06-01
影响因子：
2.5
通讯作者：
Tokudome, S.
中科院分区：
文献类型：
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作者：
Hattori, N.;Hayashi, T.;Tokudome, S.
为了评估耐力运动引起的氧化应激 (OS)，我们测定了 70 名完成为期两天的超级马拉松比赛的日本男性业余跑步者的血清活性氧 (ROS) 浓度。在三个时间点分析血清 ROS 水平：赛前（基线）、第一天比赛后（赛中）和第二天比赛后（目标）（赛后）。 ROS的平均值(SE)分别为151.4(3.7)(U.CARR.)、168.7(4.4)和156.8(4.4)。在三个比赛点，年龄和血清 ROS 浓度之间存在显着的正向趋势（全部 p < 0.05）。调整年龄、BMI 和平均每月跑步距离后，基线血清 ROS 浓度与第一天比赛的完成时间呈正相关，特别是 (p < 0.05)，这表明该浓度可以预测身体表现。 ROS 产生在比赛中期增加（p < 0.05），但在赛后水平恢复到基线水平，表明抗氧化防御系统可能在赛后发展以减少 OS。
To assess oxidative stress (OS) induced by endurance exercise, concentrations of serum reactive oxygen species (ROS) were determined in 70 Japanese male amateur runners completing a two-day ultra-marathon race. Serum ROS levels were analyzed at three time points: before the race (baseline), after the 1st day race (mid-race), and after the 2nd day race (goal) (post-race). The means (SE) of ROS were 151.4(3.7) (U. CARR.), 168.7(4.4), and 156.8(4.4), respectively. Significant positive trends were noted between age and serum ROS concentrations at the three race points (p < 0.05 for all). After adjusting for age, BMI and average monthly running distance, the baseline serum ROS concentrations were positively associated with completion times of the first-day race, in particular (p < 0.05), suggesting that the concentrations may predict physical performance. The ROS production increased at mid-race (p < 0.05), but the levels returned to baseline levels at post-race, indicating that an antioxidant defense system may develop post-race to reduce OS.