Dual-mode ultrasound phased arrays for image-guided surgery
Dual-mode ultrasound phased arrays for image-guided surgery
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DOI：
10.1177/016173460602800201
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发表时间：
2006-04-01
影响因子：
2.3
通讯作者：
Shrestha, Ajay
中科院分区：
文献类型：
--
作者：
Ebbini, Emad S.;Yao, Hui;Shrestha, Ajay
介绍了一种具有治疗和成像功能的单元、1 MHz双模阵列样机。给出了DMUA治疗手术野(ThxOF)和成像视场(IxFOV)的模拟和实验结果。此外，还给出了使用DMUA成像的一些特殊考虑，并使用线靶阵列和商业、质量保证模体进行了实验说明。这些结果证明了在影像引导手术中使用DMUA的潜在最强大的优势；即成像和治疗坐标系之间的内在配准。我们还介绍了在新切除的组织中，离散的和体积的HIFU损伤前后的成像结果。DMUA图像一致地显示病变形成后回声的变化，其形状和范围反映了病变的实际形状。虽然回声的改变不能作为HIFU引起的不可逆组织损伤的指标，但它们可以为预期损伤的位置和范围提供重要的反馈。因此，结合DMUA的自配准特性，病变图像有望提供对治疗性HIFU光束的组织响应的即时和空间准确的反馈。根据这里提供的结果，DMUA的成像能力可以为其他形式的图像引导添加独特的功能，例如MRI、CT和诊断超声。
A 64-element, 1 MHz prototype dual-mode array (DMUA) with therapeutic and imaging capabilities is described. Simulation and experimental results for the characterization of the therapeutic operating field (ThxOF) and imaging field-of-view (IxFOV) for a DMUA are given. In addition, some of the special considerations for imaging with DMUAs are given and illustrated experimentally using wire-target arrays and commercial, quality-assurance phantoms. These results demonstrate what is potentially the most powerful advantage of the use of DMUAs in image-guided surgery; namely, inherent registration between the imaging and therapeutic coordinate systems. We also present imaging results before and after discrete and volumetric HIFU-induced lesions in freshly-excised tissues. DMUA images consistently show changes in echogenicity after lesion formation with shape and extent reflecting the actual shape of the lesion. While changes in echogenicity cannot be used as an indicator of irreversible HIFU-induced tissue damage, they provide important feedback on the location and extent of the expected lesion. Thus, together with the self-registration property of DMUAs, lesion images can be expected to provide immediate and spatially-accurate feedback on the tissue response to the therapeutic HIFU beams. Based on the results provided here, the imaging capabilities of DMUAs can add unique features to other forms of image guidance, e.g. MRI, CT and diagnostic ultrasound.