SELECTION FOR BACTERIOPHAGE LATENT PERIOD LENGTH BY BACTERIAL DENSITY - A THEORETICAL-EXAMINATION
SELECTION FOR BACTERIOPHAGE LATENT PERIOD LENGTH BY BACTERIAL DENSITY - A THEORETICAL-EXAMINATION
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DOI：
10.1007/bf02030117
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发表时间：
1989-01-01
影响因子：
3.6
通讯作者：
ABEDON, ST
中科院分区：
文献类型：
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作者：
ABEDON, ST
在噬菌体(噬菌体)中，快速高效的胞内后代生产具有明显的好处。短潜伏期不是这样的。在其他条件相同的情况下，潜伏期越长，宿主细胞资源的利用越充分。利用已建立的噬菌体生长参数，模拟了三个连续的噬菌体裂解循环。我发现，宿主细胞密度高，但不低，可以选择较短的噬菌体潜伏期。这是因为潜伏期短的噬菌体在高寄主细胞浓度下更快地建立多个平行感染，而潜伏期长的噬菌体在同一时期仅限于在单个细胞内生长。这意味着潜伏期短的噬菌体习惯性地生长在宿主细胞丰富的环境中。
In bacteriophage (phage), rapid and efficient intracellular progeny production is of obvious benefit. A short latent period is not. All else being equal, a longer latent period utilizes host cell resources more completely. Using established parameters of phage growth, a simulation of three successive phage lysis cycles is presented. I have found that high, but not low, host cell densities can select for short phage latent periods. This results from phage with short latent periods more rapidly establishing multiple parallel infections at high host cell concentrations, whereas phage with long latent periods are restricted to growth within a single cell over the same period. This implies that phage with short latent periods habitually grow in environments that are rich in host cells.