Neural correlates of cross-modal binding
Neural correlates of cross-modal binding
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DOI：
10.1038/nn993
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发表时间：
2003-02-01
影响因子：
25
通讯作者：
Hallett, M
中科院分区：
文献类型：
--
作者：
Bushara, KO;Hanakawa, T;Hallett, M
大脑是如何将来自多种感觉方式的信号结合在一起，以产生对外部世界中的物体和事件的统一感知的，对此我们知之甚少。使用事件相关的功能磁共振成像（fMRI）在人类中，我们测量了短暂的大脑反应听觉/视觉结合，证明了声音引起的视觉运动感知的变化。相同的听觉和视觉刺激在所有的试验中，但在一些试验中，他们被认为是绑定在一起，在其他人被认为是未绑定的单峰事件。跨模态结合与高活性在多模态领域，但较低的活动，主要是单峰地区。这种激活模式表明，一个互惠和竞争性的多模态和单峰领域之间的相互作用的基础上的感知解释同时从多个感官形式的信号。
Little is known about how the brain binds together signals from multiple sensory modalities to produce unified percepts of objects and events in the external world. Using event-related functional magnetic resonance imaging (fMRI) in humans, we measured transient brain responses to auditory/visual binding, as evidenced by a sound-induced change in visual motion perception. Identical auditory and visual stimuli were presented in all trials, but in some trials they were perceived to be bound together and in others they were perceived as unbound unimodal events. Cross-modal binding was associated with higher activity in multimodal areas, but lower activity in predominantly unimodal areas. This activation pattern suggests that a reciprocal and 'competitive' interaction between multimodal and unimodal areas underlies the perceptual interpretation of simultaneous signals from multiple sensory modalities.