Human skin condition and its associations with nutrient concentrations in serum and diet
Human skin condition and its associations with nutrient concentrations in serum and diet
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DOI：
10.1093/ajcn/77.2.348
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发表时间：
2003-02-01
影响因子：
7.1
通讯作者：
Roza, L
中科院分区：
文献类型：
--
作者：
Boelsma, E;van de Vijver, LP;Roza, L
背景：营养因子在皮肤上发挥着有希望的作用，但只有很少的信息可用于营养素的生理浓度对人类皮肤状况的调节作用。目的：目的是评估血清和饮食中的营养浓度是否与人类的皮肤状况有关。设计：进行了一项横断面研究，其中获得了302名健康男性和女性的血清营养物质浓度、营养物质膳食摄入量、皮肤水合作用、皮脂含量和表面pH值的数据。使用无创技术测量皮肤状况。膳食摄入量通过2份辅食频率问卷进行评估。采用多元回归分析评价血清维生素和类胡萝卜素以及膳食微量和大量营养素与皮肤状况的关系。结果：在调整了潜在的混杂因素（包括性别、年龄和吸烟）后，在总人口中，血清维生素A与皮肤皮脂含量和表面pH值之间以及饮食中总脂肪、饱和脂肪、单不饱和脂肪和皮肤水合作用之间存在统计学上显著的关联。单不饱和脂肪摄入量也与表面pH值有关。血清-隐黄质与皮肤水合作用之间以及表面pH值与液体和钙摄入量之间的关系仅在男性中观察到。结论：观察到血清、饮食和皮肤状况之间的几种关联，表明基线营养状况的变化可能影响皮肤状况。
Background: Nutritional factors exert promising actions on the skin, but only scant information is available on the modulating effects of physiologic concentrations of nutrients on the skin condition of humans.Objective: The objective was to evaluate whether nutrient concentrations in serum and diet are associated with the skin condition of humans.Design: A cross-sectional study was conducted in which data on serum concentrations of nutrients, dietary intake of nutrients, and the hydration, sebum content, and surface pH of skin were obtained from 302 healthy men and women. Skin condition was measured with the use of noninvasive techniques. Dietary intake was assessed with 2 complementary food-frequency questionnaires. Multiple regression analysis was used to evaluate associations of serum vitamins and carotenoids and of dietary micro- and macronutrients with skin condition.Results: After adjustment for potential confounders, including sex, age, and smoking, statistically significant associations were shown in the total population between serum vitamin A and skin sebum content and surface pH and between the dietary intake of total fat, saturated fat, monounsaturated fat, and skin hydration. Monounsaturated fat intake was also associated with surface pH. Associations between serum beta-cryptoxanthin and skin hydration and between surface pH and fluid and calcium intakes were observed in men only.Conclusion: Several associations between nutrients in serum and diet and skin condition were observed, indicating that changes in baseline nutritional status may affect skin condition.