Microfluidic valves comprising nanolayered thermoresponsive polymer-grafted capillaries
Microfluidic valves comprising nanolayered thermoresponsive polymer-grafted capillaries
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DOI：
10.1002/adma.200402068
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发表时间：
2005-11-18
影响因子：
29.4
通讯作者：
Okano, T
中科院分区：
文献类型：
--
作者：
Idota, N;Kikuchi, A;Okano, T
使用接枝到毛细管腔表面上的热敏聚合物进行热调节流量控制，有助于快速、可靠和可重复的开闭循环（见图）。内表面上的接枝聚合物链的水合可以增加壁界面处的水合层的微粘度，而不会物理地阻塞管腔，从而在与微流体方法相关的流体静压下在微通道中产生完全和可逆的开/关流动阀。
Thermally regulated flow control using a thermoresponsive polymer grafted onto surfaces of capillary lumen facilitates rapid, reliable, and repeatable open-close cycles (see Figure). Hydration of the grafted polymer chains on the internal surfaces may increase the microviscosity of the hydration layers at the wall interfaces without physically occluding the lumen, producing complete and reversible on/off flow valving in microchannels under hydrostatic pressures relevant for microfluidics approaches.