Alternating co-synthesis of glycol nucleic acid (GNA) monomers with dicarboxylic acids via drying
Alternating co-synthesis of glycol nucleic acid (GNA) monomers with dicarboxylic acids via drying
复制标题
通过干燥交替共合成乙二醇核酸 (GNA) 单体与二羧酸
DOI：
10.1039/d2cc06818d
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发表时间：
2023
影响因子：
4.9
通讯作者：
Cleaves II H. James
中科院分区：
文献类型：
--
作者：
Yi Ruiqin;Jia Tony Z;Meringer Markus;Marshall Luke K.;Chen Chen;McGlynn Shawn E;Fahrenbach Albert C.;Cleaves II H. James
我们报告了在合理的早期地球含水干燥条件下，乙二醇核酸（GNA）单体与未取代和取代的二羧酸连接体的共聚反应。生产线性和支化共聚物。机制方面的反应和潜在的作用，这些聚合物在益生元化学进行了讨论。
We report the co-polymerization of glycol nucleic acid (GNA) monomers with unsubstituted and substituted dicarboxylic acid linkers under plausible early Earth aqueous dry-down conditions. Both linear and branched co-polymers are produced. Mechanistic aspects of the reaction and potential roles of these polymers in prebiotic chemistry are discussed.