Deficit of social cognition in subjects with surgically treated frontal lobe lesions and in subjects affected by schizophrenia
Deficit of social cognition in subjects with surgically treated frontal lobe lesions and in subjects affected by schizophrenia
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接受手术治疗的额叶病变的受试者和精神分裂症受试者的社会认知缺陷
DOI：
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发表时间：
2006
影响因子：
4.7
通讯作者：
R. Galzio
中科院分区：
文献类型：
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作者：
M. Mazza;C. Costagliola;V. di Michele;Vincenzo Magliani;R. Pollice;A. Ricci;Emanuela Di Giovanbattista;R. Roncone;M. Casacchia;R. Galzio
人类通过将欲望和信念等独立心理状态归因于他人来预测和解释他人行为的能力，被认为是由于我们构建“心理理论”的能力。最近，几项神经影像学研究表明，内侧额叶在人脑专用的“心智化”或“心理理论”网络中发挥着关键作用。在这项研究中，我们将左右内侧前额叶病变患者在心理理论和社会认知任务中的表现与精神分裂症患者进行了比较。我们报告了前额叶病变患者和精神分裂症患者在理解错误信念、理解社会情境和使用战术策略方面具有相似的社会认知特征。这些发现与“心智理论”的功能解剖学相关。
The ability of humans to predict and explain other people’s behaviour by attributing independent mental states such as desires and beliefs to them, is considered to be due to our ability to construct a “Theory of Mind”. Recently, several neuroimaging studies have implicated the medial frontal lobes as playing a critical role in a dedicated “mentalizing” or “Theory of Mind” network in the human brain. In this study we compare the performance of patients with right and left medial prefrontal lobe lesions in theory of mind and in social cognition tasks, with the performance of people with schizophrenia.We report a similar social cognitive profile between patients with prefrontal lobe lesions and schizophrenic subjects in terms of understanding of false beliefs, in understanding social situations and in using tactical strategies. These findings are relevant for the functional anatomy of “Theory of Mind”.
影响因子：
17.7
作者：
Calarge, C;Andreasen, NC;O'Leary, DS
通讯作者：
O'Leary, DS