Photoluminescence properties of sonochemically synthesized gold nanoparticles for DNA biosensing
Photoluminescence properties of sonochemically synthesized gold nanoparticles for DNA biosensing
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DOI：
10.1016/j.saa.2010.03.010
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发表时间：
2010-07-01
影响因子：
4.4
通讯作者：
Ashokkumar, Muthupandian
中科院分区：
文献类型：
--
作者：
Anandan, Sambandam;Oh, Seung-Do;Ashokkumar, Muthupandian
利用激光扫描共聚焦显微镜研究了声化学法合成的金纳米粒子与AT-和GC-DNA的电子相互作用，测量了Au纳米粒子与单个DNA分子的光致发光（PL）光谱特性和固有的PL图像。掺入AT-DNA和GC-DNA的Au纳米粒子呈现共聚焦PL图像。这些结果表明Au纳米颗粒与DNA之间存在刘易斯酸（Au）-刘易斯碱（DNA的N-或O-基团）类型的相互作用。(C)2010年爱思唯尔。All rights reserved.
The electronic interactions of sonochemically synthesized gold (Au) nanoparticles with AT- and GC-DNA were studied by measuring photoluminescence (PL) spectral properties and the inherent PL images of the Au nanoparticles incorporated with the single DNA molecules using a laser scanning confocal microscope. The Au-nanoparticles incorporated AT-DNA and GC-DNA exhibit confocal PL image. These results suggest a Lewis acid (Au)-Lewis base (N- or O-groups of DNA) type of interaction between Au nanoparticles and DNA. (C) 2010 Elsevier By. All rights reserved.