Phthalate monoesters levels in the urine of young children

Phthalate monoesters levels in the urine of young children
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DOI:
10.1007/s00128-001-0255-z
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发表时间:
2002-03-01
影响因子:
2.7
通讯作者:
Hilborn, ED
Hilborn, ED
中科院分区:
环境科学与生态学4区
文献类型:
--
作者:
Brock, JW;Caudill, SP;Hilborn, ED

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本文主要研究儿童尿液中邻苯二甲酸单酯的含量。邻苯二甲酸酯是一种普遍存在的工业化学品,用于消费品、塑料和农药配方。邻苯二甲酸酯作为活性成分或非活性成分被包括在农药配方中。人类和啮齿动物将邻苯二甲酸双酯代谢成相应的单羧酸衍生物,通常称为单酯,它是葡萄糖醛酸化的,并在尿液和/或粪便中排泄。由于儿童的行为和解剖学特征,人们普遍认为儿童暴露在环境污染物中的风险更大。
This article focuses on phthalate monoesters levels in the urine of young children. Phthalates are ubiquitous industrial chemicals used in consumer products, in plastics and in pesticide formulations. Phthalates have been included in pesticide formulations as both active or inactive ingredients. Humans and rodents metabolize phthalate di esters to the corresponding mono carboxylic acid derivative, commonly called the mono ester, which is glucuronidated and excreted in urine and/or feces. Children are generally recognized as being at risk for greater exposure to environmental contaminants because of behavioral and anatomic characteristics.