High-resolution Diffusion Tensor Imaging for the Detection of Diffusion Abnormalities in the Trigeminal Nerves of Patients with Trigeminal Neuralgia Caused by Neurovascular Compression
High-resolution Diffusion Tensor Imaging for the Detection of Diffusion Abnormalities in the Trigeminal Nerves of Patients with Trigeminal Neuralgia Caused by Neurovascular Compression
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DOI：
10.1111/j.1552-6569.2010.00508.x
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发表时间：
2011-04-01
影响因子：
2.4
通讯作者：
Ogasawara, Kuniaki
中科院分区：
文献类型：
--
作者：
Fujiwara, Shunrou;Sasaki, Makoto;Ogasawara, Kuniaki
PURPOSETo detect diffusion abnormalities in the trigeminal nerves of patients with trigeminal neuralgia (TN) caused by neurovascular compression (NVC) by using a high-resolution diffusion tensor imaging (HR-DTI) technique.METHODSThirteen patients with TN and 14 healthy controls underwent HR-DTI scanning. After extracting the trigeminal nerve using a tractography technique, we measured the fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and compared the contralateral ratios (CR) of these parameters between the patients and controls, and correlated these ratios with the cross-sectional areas of the nerves.RESULTSThe CRs of the FA values for the trigeminal nerves of the patients (1.00 +/- 0.15) had significantly higher variance than those of healthy controls (1.00 +/- 0.05) (P < .05) and showed a positive correlation with the cross-sectional area of the nerves (r = 0.81). In contrast, the CRs of the ADC values were not significantly different between the two groups (1.02 +/- 0.10 and 1.01 +/- 0.08, respectively) and had no significant correlation with cross-sectional area.CONCLUSIONHR-DTI can detect an alteration in the relative FA values of affected trigeminal nerves and a correlation with atrophic changes in patients with NVC-induced TN.
