Gene-panel sequencing and the prediction of breast-cancer risk.
Gene-panel sequencing and the prediction of breast-cancer risk.
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DOI:
10.1056/nejmsr1501341
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发表时间:
2015-06-04
期刊:
影响因子:
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通讯作者:
Foulkes WD
中科院分区:
文献类型:
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作者:
Easton DF;Pharoah PD;Antoniou AC;Tischkowitz M;Tavtigian SV;Nathanson KL;Devilee P;Meindl A;Couch FJ;Southey M;Goldgar DE;Evans DG;Chenevix-Trench G;Rahman N;Robson M;Domchek SM;Foulkes WD
An international group of cancer geneticists review the level of evidence for the association of gene variants with the risk of breast cancer. It is difficult to draw firm conclusions from the data because of ascertainment bias and the lack of data from large populations.