Liver Transplantation for Biliary Atresia: Is There a Difference in Outcome for Infants?
Liver Transplantation for Biliary Atresia: Is There a Difference in Outcome for Infants?
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DOI：
10.1097/mpg.0000000000000986
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发表时间：
2016-02-01
影响因子：
2.9
通讯作者：
Shneider, Benjamin L.
中科院分区：
文献类型：
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作者：
Arnon, Ronen;Annunziato, Rachel A.;Shneider, Benjamin L.
目的：肝移植治疗儿童胆道闭锁(BA)常因胆汁引流困难、胆汁性肝硬变并发症或反复胆管炎等原因而行。Kasai肝门肠吻合术后胆汁引流不良是婴幼儿肝移植的主要原因。本研究的目的是比较首次隔离肝移植治疗2岁前的BA婴儿(在婴儿期移植[TAI])和以后移植的儿童(2岁)的临床特征和结果。
Objectives:Liver transplantation (LT) in children with biliary atresia (BA) is often performed because of poor bile drainage, complications of biliary cirrhosis, or recurrent cholangitis. Poor bile drainage after a Kasai hepatoportoenterostomy is the primary driver for LT in infancy. The aim of the present study was to compare the clinical characteristics and outcome of first isolated liver transplantation for infants with BA who underwent transplant before 2 years of age (transplanted at infancy [TAI]) with children transplanted later in life (age 2-