Soluble B7‐H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia
Soluble B7‐H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia
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DOI：
10.1111/aji.12988
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发表时间：
2018-09
影响因子：
3.6
通讯作者：
P. Mach;Luisa Nolte-Boenigk;L. Droste;L. Fox;M. Frank;B. Schmidt;F. Herse;S. Verlohren;L. Wicherek;A. Iannaccone;C. Birdir;D. Andrikos;R. Kimmig;A. Gellhaus;A. Köninger
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文献类型：
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作者：
P. Mach;Luisa Nolte-Boenigk;L. Droste;L. Fox;M. Frank;B. Schmidt;F. Herse;S. Verlohren;L. Wicherek;A. Iannaccone;C. Birdir;D. Andrikos;R. Kimmig;A. Gellhaus;A. Köninger
B7-H4负性调节T细胞介导的免疫功能，可能在子痫前期(PE)中起重要作用。在这里，我们研究了PE与母体可溶性B7-H4(SB7-H4)血清水平和胎盘中B7-H4mRNA表达的关系。
B7‐H4 negatively regulates T‐cell‐mediated immunity and might play an important role in preeclampsia (PE). Here, we have investigated the association between PE and maternal soluble B7‐H4 (sB7‐H4) serum levels and B7‐H4 mRNA expression in the placenta.