Two-component signaling circuit structure and properties.

Two-component signaling circuit structure and properties.
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DOI:
10.1016/j.mib.2010.01.009
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发表时间:
2010-04
影响因子:
5.4
通讯作者:
Goulian, Mark
Goulian, Mark
中科院分区:
生物学2区
文献类型:
--
作者:
Goulian, Mark

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各种建模和实验研究已经分析了双组分系统中的反应,互连和图案,着眼于理解它们的生理含义和替代设计之间的差异。最近取得进展的例子包括自动调节、分支通路中的信号整合、串扰抑制和通过连接蛋白的交叉调节。
Various modeling and experimental studies have analyzed the reactions, interconnections, and motifs in two-component systems, with an eye towards understanding their physiological implications and the differences between alternative designs. Examples where recent progress has been made include aspects of autoregulation, signal integration in branched pathways, cross-talk suppression, and cross-regulation via connector proteins.
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