Proteins and mucoproteins in the duodenal fluids of cystic fibrosis and control subjects.
Proteins and mucoproteins in the duodenal fluids of cystic fibrosis and control subjects.
复制标题
囊性纤维化和对照受试者十二指肠液中的蛋白质和粘蛋白。
DOI：
10.1016/0009-8981(68)90332-x
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发表时间：
1968
期刊：
影响因子：
--
通讯作者：
J. Adams
中科院分区：
文献类型：
--
作者：
R. E. Knauff;J. Adams
通过定量纸带电泳分析囊性纤维化患者和对照组十二指肠液的蛋白质和粘蛋白。两个受试者组的9种主要蛋白质和粘蛋白质之间存在显著的定量差异，其中3种蛋白质和2种粘蛋白质组间无差异，但另外2种蛋白质和2种粘蛋白质组间存在差异。囊性纤维化受试者有：（1）粘蛋白O和蛋白C5相对过量;（2）粘蛋白C4和蛋白O相对缺乏。值得注意的是，囊性纤维化的特征是定量差异模式，而不是aqualitative差异。
Duodenal fluids from cystic fibrosis and control subjects were analyzed for proteins and mucoproteins by quantitative paper-strip electrophoresis. Prominent quantitative differences were found among the nine major proteins and mucoproteins of the two subject groups.Three proteins and two mucoproteins did not differ between the groups, but the other two proteins and two mucoproteins did differ. The cystic fibrosis subjects had: (I) a relative excess of substances designated as mucoprotein O and protein C5; and (2) a relative deficiency of mucoprotein C4and protein O.It is notable that cystic fibrosis is characterized by aquantitativedifference pattern rather than by aqualitativedifference.