MULTIPLE GENETIC-CONTROL OF ACETATE-INDUCED OLFACTORY RESPONSES IN DROSOPHILA-MELANOGASTER LARVAE
MULTIPLE GENETIC-CONTROL OF ACETATE-INDUCED OLFACTORY RESPONSES IN DROSOPHILA-MELANOGASTER LARVAE
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DOI：
10.1038/hdy.1994.192
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发表时间：
1994-10-01
期刊：
影响因子：
3.8
通讯作者：
DANNET, F
中科院分区：
文献类型：
--
作者：
COBB, M;DANNET, F
用8种脂肪族It-乙酸酯（甲基醋酸酯）的同系物对果蝇幼虫的嗅觉刺激进行了行为反应的测定。乙酸辛酯）和顺式乙酸异辛酯。幼虫往往被吸引到短链乙酸酯（甲基）。戊基）并被较长链的乙酸酯（乙酸己酯、乙酸庚酯和乙酸辛酯）排斥。无论研究的剂量如何，所有幼虫都强烈地被乙酸丙酯吸引。幼虫的嗅觉反应一般随着年龄的增长而下降。两个地理株表现出特异性的染色体缺失。胜沼（日本）幼虫乙酸己酯没有表现出任何反应，染色体置换显示这种行为是由染色体II上的基因控制。Tai（象牙海岸）幼虫对乙酸戊酯没有反应;染色体置换表明，主要涉及X染色体和III染色体上的两个遗传因素。该反应由染色体II调节。没有发现Y染色体的影响。研究了两种嗅觉突变体，olfC（X染色体）和Indf（III染色体）;这两种突变体对某些醋酸盐均表现出异常反应。结果进行了讨论，在各种模型的嗅觉处理和这些模型的影响，参与嗅觉的基因的数量。
Behavioural responses of Drosophila melanogaster larvae were measured in response to olfactory stimulation with an homologous series of eight aliphatic It-acetates (methyl...octyl actetate) and with cis-vaccenyl acetate. Larvae tended to be attracted to short-chain acetates (methyl...pentyl) and repelled by longer chain acetates (hexyl, heptyl and octyl acetate). All larvae were strongly attracted to propyl acetate, irrespective of the dose studied. Larval olfactory responses generally declined with age. Two geographical strains showed specific anosmias. Katsunuma (Japan) larvae showed no response to hexyl acetate; chromosome substitution showed this behaviour to be controlled by genes on chromosome II. Tai (Ivory Coast) larvae showed no response to pentyl acetate; chromosome substitution showed that two genetic factors were primarily involved, on the X chromosome and chromosome III. The response was modulated by chromosome II. No effect of the Y chromosome was found. Two olfactory mutants were studied, olfC (X chromosome) and Indf (chromosome III); both mutants showed abnormal responses to certain acetates. The results are discussed in terms of various models of olfactory processing and the implications of these models for the number of genes involved in olfaction.