Evaluation of a rapid latex slide agglutination test for herpes simplex virus as a specimen screen and culture identification method

Evaluation of a rapid latex slide agglutination test for herpes simplex virus as a specimen screen and culture identification method
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单纯疱疹病毒快速乳胶玻片凝集试验作为标本筛选和培养物鉴定方法的评价

DOI:
10.1128/jcm.25.5.936-937.1987
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发表时间:
1987
影响因子:
9.4
通讯作者:
K. Schneck
K. Schneck
中科院分区:
医学2区
文献类型:
--
作者:
D. Halstead;D. Beckwith;R. Sautter;L. Plosila;K. Schneck

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使用Virogen疱疹载玻片试验(Wampole Laboratories,Div.卡特-华莱士公司,克兰伯里,新泽西州),一种快速乳胶凝集法结果进行了比较,与单纯疱疹病毒的细胞培养分离,然后用免疫过氧化物酶或荧光试剂鉴定。直接试验的敏感性、特异性、阳性和阴性预测值分别为49.7%、93.4%、96.0%和37.1%。乳胶凝集试验的敏感性和特异性培养确认分别为75.9%和100%。
A total of 449 clinical specimens and 199 culture fluids were tested using the Virogen Herpes Slide Test (Wampole Laboratories, Div. Carter-Wallace, Inc., Cranbury, N.J.), a rapid latex agglutination procedure. The results were compared with those obtained with isolation of herpes simplex virus in cell culture followed by identification using immunoperoxidase or fluorescent reagents. The sensitivity, specificity, and positive and negative predictive values of the direct test were 49.7, 93.4, 96.0, and 37.1%, respectively. The sensitivity and specificity of the latex agglutination test for culture confirmation were 75.9 and 100%, respectively.