Microvascular Angina: Diagnosis and Management.
Microvascular Angina: Diagnosis and Management.
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微血管性心绞痛的诊断和治疗。
DOI：
10.15420/ecr.2021.15
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发表时间：
2021-03
期刊：
影响因子：
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通讯作者：
Bairey Merz CN
中科院分区：
文献类型：
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作者：
Aldiwani H;Mahdai S;Alhatemi G;Bairey Merz CN
在过去的几十年里，对疑似缺血但无阻塞性冠状动脉疾病（称为INOCA）的认识有所增加，其中一个关键因素是微血管性心绞痛。微血管性心绞痛患者发生主要不良心脏事件（包括MI、卒中、射血分数保留的心力衰竭和死亡）的风险较高，但迄今为止尚无明确的循证诊断和治疗指南。最近，冠状动脉血管运动障碍国际研究小组提出了使用侵入性和非侵入性方法诊断微血管性心绞痛的标准化标准。管理策略仍然是经验性的，主要是由于缺乏高水平的证据为基础的指南和临床试验。在这篇综述中，作者将阐述微血管性心绞痛诊断的最新方法，并讨论该疾病患者的循证药物和非药物治疗。
Recognition of suspected ischaemia with no obstructive coronary artery disease – termed INOCA – has increased over the past decades, with a key contributor being microvascular angina. Patients with microvascular angina are at higher risk for major adverse cardiac events including MI, stroke, heart failure with preserved ejection fraction and death but to date there are no clear evidence-based guidelines for diagnosis and treatment. Recently, the Coronary Vasomotion Disorders International Study Group proposed standardised criteria for diagnosis of microvascular angina using invasive and non-invasive approaches. The management strategy for remains empirical, largely due to the lack of high-levelevidence- based guidelines and clinical trials. In this review, the authors will illustrate the updated approach to diagnosis of microvascular angina and address evidence-based pharmacological and non-pharmacological treatments for patients with the condition.