Fabrication of Monodisperse Poly (Allyl Glycidyl Ether-co-divinyl Benzene) Microspheres and Their Application in Anion-exchange Stationary Phase
Fabrication of Monodisperse Poly (Allyl Glycidyl Ether-co-divinyl Benzene) Microspheres and Their Application in Anion-exchange Stationary Phase
复制标题
单分散聚(烯丙基缩水甘油醚-二乙烯基苯)微球的制备及其在阴离子交换固定相中的应用
DOI：
10.1016/j.chroma.2019.02.042
复制
发表时间：
2019
影响因子：
4.1
通讯作者：
Zhu Yan
中科院分区：
文献类型：
--
作者：
Liu Junwei;Sun Yan;Wang Chaowei;Hu Kai;Jia Chunxiao;Wang Guoqing;Sun Yu an;Zhang Shusheng;Zhu Yan
采用种子溶胀聚合法制备了聚（烯丙基缩水甘油醚-co-二乙烯基苯）微球，并将其用于直接季铵化制备阴离子交换固定相。采用扫描电镜和氮气吸附-脱附法对微球的单分散性、粒径、表面形貌和孔隙率进行了表征。采用红外光谱、元素分析、穿透曲线等方法对阴离子交换固定相进行了表征，并通过分离常规阴离子和有机弱酸考察了自制阴离子交换柱的色谱性能。结果表明，烯丙基缩水甘油醚-二乙烯基苯共聚物微球在整个pH范围内（1-14）均具有良好的相容性，环氧基的存在保证了微球的上级反应活性。所制备的聚（烯丙基缩水甘油醚-co-二乙烯基苯）微球有望取代聚（苯乙烯-二乙烯基苯）和聚（甲基丙烯酸缩水甘油酯-二乙烯基苯），成为制备阴离子交换剂的新一代载体。
Micron-sized poly (allyl glycidyl ether-co-divinyl benzene) microspheres were prepared by a seed swelling and polymerization method and applied to prepare anion-exchange stationary phases by direct quaternization. The mono-dispersity, diameters, surface characteristics and porosity of microspheres were measured by scanning electron microscope and nitrogen adsorption-desorption measurements. The anion-exchange stationary phases were characterized by Fourier Transform Infrared Spectrum, Elemental Analysis, Breakthrough Curve, etc. The chromatographic properties of this self-fabricated anion-exchange column were investigated by separating conventional anions and organic weak acids. According to the results, poly (allyl glycidyl ether-co-divinyl benzene) microsphere possesses good compatibility in the whole pH range of 1–14; the presence of epoxy group guarantees the microsphere’s superior reaction activity. The prepared poly (allyl glycidyl ether-co-divinyl benzene) microsphere is promising to replace poly (styrene-divinylbenzene) and poly (glycidylmethacrylate-divinylbenzene) and becomes a generation of support for the preparation of anion exchangers.