Strength and fluoride release characteristics of a calcium fluoride based dental nanocomposite.
Strength and fluoride release characteristics of a calcium fluoride based dental nanocomposite.
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DOI：
10.1016/j.biomaterials.2008.07.037
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发表时间：
2008-11
期刊：
影响因子：
14
通讯作者：
Chow LC
中科院分区：
文献类型：
--
作者：
Xu HH;Moreau JL;Sun L;Chow LC
继发龋和修复体断裂是口腔修复中最常见的两个问题。氟离子（F）的释放可能是一个实质性的益处，因为F可以富集邻近的釉质或牙本质以对抗龋齿。本研究的目的是将新型CaF 2纳米颗粒加入牙科树脂中，以开发应力承载，F-释放纳米复合材料。CaF 2纳米粒子，在我们的实验室制备的第一次，在树脂中与增强晶须填料相结合。对于含有30%的CaF 2和35%的晶须（按质量计）的复合材料，弯曲强度（平均值± sd; n = 6）为110 ± 11 MPa。它与108 ± 19 MPa的应力承载、非释放商业复合材料（Tukey的为0.05）相匹配。含20%CaF2的复合材料10周时的累积释氟量为2.34 ± 0.26mmol/L。初始氟释放率为2 µg/（h·cm 2），10周后缓释率为0.29 µg/（h·cm 2）。这些值超过了传统和树脂改性玻璃离聚物材料的报告释放。总之，纳米复合材料被开发为具有相对高的强度以及持续释放的氟离子，这是当前材料中不可用的组合。这些强的和释放F的复合材料可以产生可减少继发龋和修复断裂的发生的漂白。
Secondary caries and restoration fracture remain the two most common problems in restorative dentistry. Release of fluoride ions (F) could be a substantial benefit because F could enrich neighboring enamel or dentin to combat caries. The objective of this study was to incorporate novel CaF2 nanoparticles into dental resin to develop stress-bearing, F-releasing nanocomposite. CaF2 nanoparticles, prepared in our laboratories for the first time, were combined with reinforcing whisker fillers in a resin. Flexural strength (mean ± sd; n = 6) was 110 ± 11 MPa for the composite containing 30% of CaF2 and 35% whiskers by mass. It matched the 108 ± 19 MPa of a stress-bearing, non-releasing commercial composite (Tukey’s at 0.05). The composite containing 20% CaF2 had a cumulative F release of 2.34 ± 0.26 mmol/L at 10 weeks. The initial F release rate was 2 µg/(h·cm2), and the sustained release rate after 10 weeks was 0.29 µg/(h·cm2). These values exceeded the reported releases of traditional and resin-modified glass ionomer materials. In summary, nanocomposites were developed with relatively high strength as well as sustained release of fluoride ions, a combination not available in current materials. These strong and F releasing composites may yield restorations that can reduce the occurrence of both secondary caries and restoration fracture.
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影响因子：
5
作者：
Lim, BS;Ferracane, JL;Condon, JR
通讯作者：
Condon, JR
影响因子：
5
作者：
DIAZARNOLD, AM;HOLMES, DC;SWIFT, EJ
通讯作者：
SWIFT, EJ
影响因子：
5
作者：
Drummond, JL;Bapna, MS
通讯作者：
Bapna, MS
DOI：
10.1002/jbm.820280205
发表时间：
1994-02-01
期刊：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
影响因子：
--
作者：
GOLDBERG, AJ;BURSTONE, CJ;JANCAR, J
通讯作者：
JANCAR, J
影响因子：
5
作者：
MATHIS, RS;FERRACANE, JL
通讯作者：
FERRACANE, JL