Implications of SARSr-CoV 2 infection in thalassemias: Do patients fall into the "high clinical risk" category?

Implications of SARSr-CoV 2 infection in thalassemias: Do patients fall into the "high clinical risk" category?
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DOI:
10.23750/abm.v91i2.9592
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发表时间:
2020-05-11
期刊:
Acta bio-medica : Atenei Parmensis
影响因子:
--
通讯作者:
De Sanctis V
De Sanctis V
中科院分区:
其他
文献类型:
--
作者:
Karimi M;De Sanctis V

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我们对冠状病毒都是盲目的,但公平地认为,地中海贫血患者是否特别容易受到SARS-COV-2感染,或者是否比正常人群更容易患COVID-19并发症,特别是当他们变老时。令人沮丧的是,目前,这种病毒仍然是新的。直到12月底才引起世界卫生组织的注意。到目前为止,地中海贫血的病例报告很少;这是由于缺乏检测还是真正缺乏感染/易感性?然而,我们认为应该收集更多数据,以更好地描述SARS-CoV-2感染对地中海贫血患者的影响。因此,有必要进行多中心登记,并收集来自阳性COVID-19重型地中海贫血和非输血依赖性地中海贫血的全面数据,以澄清有争议的问题。与此同时,在SARS-CoV-2感染高危的地中海贫血患者中,需要早期和警惕性监测沿着高质量的支持性护理。()
We’re all flying blind regarding coronavirus, but it’s fair to think if thalassemic patients are particularly vulnerable to SARS-COV-2 infection or are at potential higher risk of complications from COVID-19 than normal population, specially when they become older. The frustrating thing is that, right now, this virus is still new. It only came to the attention of the World Health Organization at the end of December. Very few cases in thalassemia have so far been reported; is this due to lack of testing or a true lack of infection/susceptibility? However, we believe that more data should be collected to better characterise the impact of SARS-CoV-2 infection in patients with thalassemias. Therefore, a multicenter registry and the collection of comprehensive data from both positive COVID-19 thalassemia major and non-transfusion dependent thalassemia are necessary to clarify debated issues. In the meantime an early and vigilant monitoring along with high quality supportive care are needed in thalassemic patients at high risk for SARS-CoV-2 infection. ()