Garlic-Derived Allyl Sulfides in Cancer Therapy
Garlic-Derived Allyl Sulfides in Cancer Therapy
复制标题
大蒜衍生的烯丙基硫醚在癌症治疗中的应用。
DOI：
10.2174/1871520614666140521120811
复制
发表时间：
2014-01-01
影响因子：
2.8
通讯作者：
Qiao, Liang
中科院分区：
文献类型：
--
作者：
Cao, Hai-Xia;Zhu, Ke-Xiang;Qiao, Liang
大蒜（Allium sativam L.）广泛用于传统草药和替代医学。大蒜的潜在健康益处很大程度上归因于其代谢副产物。广泛的体内和体外研究表明大蒜衍生物具有抗癌作用，但其潜在机制尚不完全清楚。在这篇小综述中，我们的目的是总结已报道的大蒜产品作为抗肿瘤药物的生物效应，并提出大蒜及其衍生物抗癌作用的可能分子机制。
Garlic (Allium sativam L.) is widely used in traditional herbal remedies and alternative medicine. The potential health benefits of garlic are largely attributed to its metabolic byproducts. Extensive in vivo and in vitro studies has demonstrated that the garlic derivatives possess anti-cancer effects, but the underlying mechanisms are not completely understood. In this mini-review, we aim to summarize the reported biological effects of garlic products as anti-tumor agents, and present the possible molecular mechanisms responsible for the anti-carcinogenesis effects of garlic and its derivatives.