Methylation of chicken fibroblast heat shock proteins at lysyl and arginyl residues.
Methylation of chicken fibroblast heat shock proteins at lysyl and arginyl residues.
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DOI：
10.1016/s0021-9258(18)34338-2
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发表时间：
1982-07
期刊：
影响因子：
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通讯作者：
C. Wang;E. Lazarides;C. M. O’Connor;S. Clarke
中科院分区：
文献类型：
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作者：
C. Wang;E. Lazarides;C. M. O’Connor;S. Clarke
鸡胚成纤维细胞暴露于25-50 μ g ~（-1）亚砷酸钠或热休克可导致几种多肽的合成增加，这些多肽可通过二维等电聚焦/十二烷基硫酸钠凝胶电泳解析。这些多肽中的三种（一种分子量为83，000，两种分子量为68，000，但等电点不同）在体内被甲基化（Wang，C.，戈默河H、和Lazarides，E.（1981）Proc.
Exposure of chicken embryonic fibroblasts to 25-50 p~ sodium arsenite or to heat shock results in the elevated synthesis of several polypeptides which can be resolved by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis. Three of these polypeptides (one with a molecular weight of 83,000 and two with a molecular weight of 68,000 but different isoelectric points) are methylated in vivo (Wang, C., Gomer, R. H., and Lazarides, E.(1981) Proc.