Effects of attention and emotion on face processing in the human brain: An event-related fMRI study
Effects of attention and emotion on face processing in the human brain: An event-related fMRI study
复制标题
DOI：
10.1016/s0896-6273(01)00328-2
复制
发表时间：
2001-06-01
期刊：
影响因子：
16.2
通讯作者：
Dolan, RJ
中科院分区：
文献类型：
--
作者：
Vuilleumier, P;Armony, JL;Dolan, RJ
我们使用与事件相关的功能磁共振成像来评估大脑对恐惧面孔和中性面孔的反应是否受到空间注意力的调节。在其他位置存在与任务无关的刺激的情况下，受试者在预先指定的位置完成了对刺激对的严格匹配任务。面孔或房子出人意料地出现在相关或无关的位置，而面孔要么带有恐惧的表情，要么表现出中性的表情。面孔对梭形回的激活受到注意条件的强烈影响，但左侧杏仁核对恐惧面孔的反应不受影响。恐惧面孔的右侧梭形活动大于中性面孔，与注意对该区域的影响无关。这些结果揭示了注意力和情绪对面孔加工的不同影响，杏仁核对威胁相关表情的反应不受强烈调节对面孔的梭形反应的注意力操纵的影响。
We used event-related fMRI to assess whether brain responses to fearful versus neutral faces are modulated by spatial attention. Subjects performed a demanding matching task for pairs of stimuli at prespecified locations, in the presence of task-irrelevant stimuli at other locations. Faces or houses unpredictably appeared at the relevant or irrelevant locations, while the faces had either fearful or neutral expressions. Activation of fusiform gyri by faces was strongly affected by attentional condition, but the left amygdala response to fearful faces was not. Right fusiform activity was greater for fearful than neutral faces, independently of the attention effect on this region. These results reveal differential influences on face processing from attention and emotion, with the amygdala response to threat-related expressions unaffected by a manipulation of attention that strongly modulates the fusiform response to faces.