Pharmacological management of obese child

Pharmacological management of obese child
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DOI:
10.1136/archdischild-2011-301127
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发表时间:
2013-06-01
影响因子:
1
通讯作者:
Wright, Neil
Wright, Neil
中科院分区:
医学4区
文献类型:
--
作者:
Petkar, Razia;Wright, Neil

文献摘要

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儿童超重和肥胖已成为临床医生日益常见的管理问题。本综述重点关注儿童肥胖的药物治疗。它考虑了历史治疗方法、当前可用的选择(主要是奥利司他和二甲双胍)以及一些潜在的未来治疗干预措施。讨论了肥胖的短期心理影响和长期健康影响。讨论了药物治疗可能合适的临床环境、生活方式干预的重要性以及支持其使用的证据和临床指导。
Childhood overweight and obesity are increasingly common management problems for clinicians. This review focuses on the pharmacological management of obesity in children. It considers historical treatments, the options currently available (principally orlistat and metformin) and some potential future therapeutic interventions. The short term psychological effect of obesity and longer term health impact are discussed. The clinical settings in which drug treatment may be appropriate, the importance of lifestyle interventions, and the evidence and clinical guidance that underpin their use are discussed.