Passive Smoking and Preterm Birth in Urban China

Passive Smoking and Preterm Birth in Urban China
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DOI:
10.1093/aje/kwu092
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发表时间:
2014-07-01
影响因子:
5
通讯作者:
Zhang, Yawei
Zhang, Yawei
中科院分区:
医学2区
文献类型:
--
作者:
Qiu, Jie;He, Xiaochun;Zhang, Yawei

文献摘要

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关于母亲被动吸烟与早产风险之间关系的研究得出了不一致的结论。2010年至2012年期间,在中国兰州进行了一项出生队列研究,其中包括10,095名分娩单胎活产的非吸烟女性。妊娠期间被动吸烟与极早产风险增加相关(< 32周妊娠;比值比= 1.98,95%置信区间:1.41,2.76),但与中度早产风险无关(32-36周妊娠;比值比= 0.98,95%置信区间:0.81,1.19)。极早产风险随暴露持续时间增加(趋势P = 0.0014)。三个月的暴露量没有变化。医学指征和自发性早产的相关性是一致的。总的来说,我们的研究结果支持被动吸烟和极早产风险之间的正相关。
Studies investigating the relationship between maternal passive smoking and the risk of preterm birth have reached inconsistent conclusions. A birth cohort study that included 10,095 nonsmoking women who delivered a singleton live birth was carried out in Lanzhou, China, between 2010 and 2012. Exposure to passive smoking during pregnancy was associated with an increased risk of very preterm birth (< 32 completed weeks of gestation; odds ratio = 1.98, 95% confidence interval: 1.41, 2.76) but not moderate preterm birth (32-36 completed weeks of gestation; odds ratio = 0.98, 95% confidence interval: 0.81, 1.19). Risk of very preterm birth increased with the duration of exposure (P for trend = 0.0014). There was no variability in exposures by trimester. The associations were consistent for both medically indicated and spontaneous preterm births. Overall, our findings support a positive association between passive smoking and the risk of very preterm birth.