Steroid interactions with structure and function of avian song control regions.
Steroid interactions with structure and function of avian song control regions.
复制标题
类固醇与鸟类鸣叫控制区的结构和功能的相互作用。
DOI：
10.1002/neu.480170305
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
DeVoogd,TJ
中科院分区：
文献类型：
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作者：
DeVoogd,TJ
继诺特博姆的开创性工作之后，鸣禽中参与鸣叫的大脑区域已成为多个实验室广泛研究的焦点。由于许多鸣禽物种的歌唱行为和歌唱控制区域的神经解剖结构都受到性类固醇的强烈影响，因此该系统已被视为一种理想的模型系统，在该系统中，人们可以潜在地确定类固醇如何影响神经元解剖结构，改变的解剖结构如何导致改变的生理学，以及改变的生理学如何导致歌唱的变化。在这篇评论的第一部分，我将重点关注金丝雀和斑胸草雀，因为我们对鸣叫系统的大部分了解都是从这两个物种获得的。我将描述歌唱行为、歌唱系统的组成部分、这些细胞核如何对歌唱做出贡献以及每个细胞核如何受到类固醇波动的影响。然后，我将推测提出该系统中激素与解剖学相互作用问题的新方法（我将用我自己实验室的初步数据来说明）。这篇评论将很简短，因为最近发表了对歌曲系统方面的几篇评论（Arnold，1982；Nottebohm，1984；Arnold 和 Gorski，1984；DeVoogd，1984；Konishi，1985）。
Following the pioneering work of Nottebohm, the brain regions involved in song production in songbirds have become a focus of extensive research in several laboratories. As both singing behavior and the neuroanatomy of song control regions are strongly affected by sex steroids in many songbird species, this system has become regarded as an ideal model system in which one can potentially determine how steroids affect neuronal anatomy, how altered anatomy leads to altered physiology, and how the altered physiology causes changes in singing. In the initial part of this review, I shall focus on canaries and zebra finches as most of our knowledge of the song system has been obtained from these two species. I shall describe singing behavior, the constituents of the song system, what is known of how these nuclei contribute to song, and how each is affected by steroid fluctuations. I shall then speculate on new ways of posing questions on hormone—anatomy interaction in this system (which I will illustrate with preliminary data from my own lab). This review will be brief as several reviews of aspects of the song system have recently been published (Arnold, 1982; Nottebohm, 1984; Arnold and Gorski, 1984; DeVoogd, 1984; Konishi, 1985).