Cardiorenal Syndrome: An Overview
Cardiorenal Syndrome: An Overview
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DOI：
10.1053/j.ackd.2018.08.004
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发表时间：
2018-09-01
影响因子：
2.9
通讯作者：
Di Lullo, Luca
中科院分区：
文献类型：
--
作者：
Ronco, Claudio;Bellasi, Antonio;Di Lullo, Luca
大量急性失代偿性心力衰竭患者存在不同程度的心、肾功能不全，通常心、肾原发病常累及心、肾功能不全或损伤对方。心肾综合征一词越来越多地被使用，但没有一致或公认的定义。为了包括大量的相互关联的紊乱，并强调心肾相互作用的双向性，提出了心肾综合征的新分类，包括5种亚型，反映了病理生理学，时间范围和伴随的心肾功能不全的性质。肾综合征通常可定义为心脏和肾脏的病理生理学病症，其中一个器官的急性或慢性功能障碍可诱发另一个器官的急性或慢性功能障碍。虽然心肾综合征通常被称为急性心脏病后的急性肾功能不全，但现在已明确肾功能受损可对心脏功能产生不良影响。(C)2018年由国家肾脏基金会，公司。All rights reserved.
It is well established that a large number of patients with acute decompensated heart failure present with various degrees of heart and kidney dysfunction usually primary disease of heart or kidney often involve dysfunction or injury to the other. The term cardiorenal syndrome increasingly had been used without a consistent or well-accepted definition. To include the vast array of interrelated derangements and to stress the bidirectional nature of heart-kidney interactions, a new classification of the cardiorenal syndrome with 5 subtypes that reflect the pathophysiology, the time frame, and the nature of concomitant cardiac and renal dysfunction was proposed. Cardiorenal syndrome can generally be defined as a pathophysiological disorder of the heart and kidneys, in which acute or chronic dysfunction of one organ may induce acute or chronic dysfunction to the other. Although cardiorenal syndrome was usually referred to as acute kidney dysfunction following acute cardiac disease, it is now clearly established that impaired kidney function can have an adverse impact on cardiac function. (C) 2018 by the National Kidney Foundation, Inc. All rights reserved.