Restriction-map variation in natural populations of Drosophila melanogaster: white-locus region.

Restriction-map variation in natural populations of Drosophila melanogaster: white-locus region.
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果蝇自然种群的限制性图谱变异:白色基因座区域。

DOI:
10.1093/oxfordjournals.molbev.a040467
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发表时间:
1987
影响因子:
10.7
通讯作者:
Aquadro,CF
Aquadro,CF
中科院分区:
生物学1区
文献类型:
--
作者:
Langley,CH;Aquadro,CF

文献摘要

被引文献

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Restriction-map variation among 38 chromosomes collected from natural populations from around the world was surveyed using probes for a 45-kb region containing and surrounding the white locus. Insertion and deletion variation was more common in the regions flanking the white transcriptional unit, and restriction-site polymorphism appears to be most common 5' of the white locus. The frequencies of individual large insertions (suspected transposable elements) were low, although 37% of the chromosomes had at least one insertion in the white-locus region. The estimated level of nucleotide heterozygosity over the whole region was 0.012. There was little linkage disequilibrium among the polymorphic sites. In contrast to earlier reports of the variation in other regions of the Drosophila melanogaster genome, there seemed to be less linkage disequilibrium and perhaps more nucleotide polymorphism.