Body mass index and mortality in nonsmoking older adults: The cardiovascular health study
Body mass index and mortality in nonsmoking older adults: The cardiovascular health study
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DOI：
10.2105/ajph.88.4.623
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发表时间：
1998-04-01
影响因子：
12.7
通讯作者：
Rossi, M
中科院分区：
文献类型：
--
作者：
Diehr, P;Bild, DE;Rossi, M
目标。本研究评估了4317名年龄在65至100岁之间的不吸烟男性和女性的体重指数与5年死亡率的关系。进行了逻辑回归分析，预测死亡率作为基线体重指数的函数，调整了人口统计学、临床和实验室协变量。体重指数与死亡率呈负相关；体重最轻的人死亡率更高。协变量的纳入对这些结果影响不大。50岁以后体重减少10%以上的人死亡率相对较高。当该群体被排除在外时，身体质量指数与死亡率之间没有剩余的关系。高体重指数与死亡率之间的关联通常在中年人群中发现，但在这个大型老年人队列中没有观察到。超重似乎不是这个年龄组5年死亡率的危险因素。相反，与显著减肥相关的风险应该是首要关注的问题。
Objectives. This study assesses the relationship of body mass index to 5-year mortality in a cohort of 4317 nonsmoking men and women aged 65 to 100 years.Methods. Logistic regression analyses were conducted to predict mortality as a function of baseline body mass index, adjusting for demographic, clinical, and laboratory covariates.Results. There was an inverse relationship between body mass index and mortality; death rates were higher for those who weighed the least. Inclusion of covariates had trivial effects on these results. People who had lost 10% or more of their body weight since age 50 had a relatively high death rate. When that group was excluded, there was no remaining relationship between body mass index and mortality.Conclusions. The association between higher body mass index and mortality often found in middle-aged populations was not observed in this large cohort of older adults. Overweight does not seem to be a risk factor for 5-year mortality in this age group. Rather, the risks associated with significant weight loss should be the primary concern.