Primary pulmonary adenoid cystic carcinoma:: Report of a case diagnosed by fine-needle aspiration cytology
Primary pulmonary adenoid cystic carcinoma:: Report of a case diagnosed by fine-needle aspiration cytology
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DOI：
10.1002/dc.10422
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发表时间：
2004-01-01
影响因子：
1.3
通讯作者：
Logroño, R
中科院分区：
文献类型：
--
作者：
Qiu, SM;Nampoothiri, MM;Logroño, R
下呼吸道腺样囊性癌是一种少见的肿瘤，可发生在主干支气管处，常表现为支气管腔内肿块，导致阻塞性肺不张和肺炎。脱落细胞学在诊断原发性支气管腺样囊性癌中很少有用，因为这些肿瘤通常位于粘膜下，粘膜通常完好无损。由于大多数支气管腺样囊性癌是内窥镜下可见的，支气管镜引导下的细针抽吸是建立病理诊断的一个很好的方法。原发性肺腺样囊性癌的细针吸取细胞学检查很少被描述。我们报告一例原发的肺腺样囊性癌，具有特征性的细胞学特征，并与计算机断层扫描、支气管镜检查和组织学结果相关联。支气管镜引导下的抽吸细胞学提供了腺样囊性癌的确凿诊断，而肺切除标本的组织学进一步证实了这一点。
Adenoid cystic carcinoma of the lower respiratory tract is an uncommon tumor that can arise in the mainstem bronchus and often presents as an endobronchial mass lesion causing bronchial obstruction with post obstructive atelectasis and pneumonia. Exfoliative cytology is seldom useful in the diagnosis of primary bronchial adenoid cystic carcinoma, because these neoplasms usually have a submucosal location with often intact mucosa. Since most endobronchial adenoid cystic carcinomas are endoscopically visible, bronchoscope-guided fine-needle aspiration constitutes an excellent approach to establish a pathologic diagnosis. The fine-needle aspiration cytology of primary pulmonary adenoid cystic carcinoma has been rarely described. We report a case of primary adenoid cystic carcinoma of the lung having characteristic cytologic features and correlate with computed tomography, bronchoscopic, and histological findings. Bronchoscope-guided aspiration cytology provided a conclusive diagnosis of adenoid cystic carcinoma, which was further corroborated by histology in the pneumonectomy specimen.