Classification aided analysis of oscillatory signatures in controlled retrieval.
Classification aided analysis of oscillatory signatures in controlled retrieval.
复制标题
受控检索中振荡特征的分类辅助分析。
DOI：
10.1016/j.neuroimage.2013.06.077
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发表时间：
2014
期刊：
影响因子：
5.7
通讯作者：
Curran,Tim
中科院分区：
文献类型：
--
作者：
Ketz,Nicholas;O'Reilly,RandalC;Curran,Tim
控制过程对于促进和抑制记忆提取都是至关重要的，但这些过程并没有得到很好的理解。目前的工作，灵感来自类似的功能磁共振成像设计（Detre等人，使用一种改进的思考/不思考（TNT）范式来研究意志对增强和抑制记忆提取的神经特征。之前的研究表明，当在线索回忆中重新研究熟悉的刺激对时（“回忆或思考所研究的配对项目”），记忆会增强，而当在线索抑制中重新研究时（“避免思考所研究的配对项目”），记忆会退化。我们使用基于类别（面孔与场景）的脑电图信号的多变量分类，以确定是否成功检索或抑制个别目标项目。基于分类器输出的逻辑回归确定，在线索回忆/抑制期间的检索激活是后续记忆的预测因子。与其名义上的思考与不思考条件相反，用这种内部措施进行标签试验，揭示了成功线索提取的增强记忆和线索抑制的退化记忆的经典TNT模式。这种分类过程使一个更有选择性的调查控制检索的时间-频率特征。比较控制检索与控制抑制，结果显示更突出的Theta振荡（3至8 Hz）在控制检索。β振荡（12至30 Hz）参与了高水平的控制提取和抑制，这表明它可能具有更普遍的控制相关作用。这些结果表明，这些频带在检索过程中的独特作用。
Control processes are critical for both facilitating and suppressing memory retrieval, but these processes are not well understood. The current work, inspired by a similar fMRI design (Detre et al., in press), used a modified Think/No-Think(TNT) paradigm to investigate the neural signatures of volition over enhancing and suppressing memory retrieval. Previous studies have shown memory enhancement when well-learned stimulus pairs are restudied in cued recall (“Recall or think of studied pair item”), and degradation when restudied with cued suppression (“Avoid thinking of studied pair item”). We used category-based (faces vs. scenes) multivariate classification of electroencephalography signals to determine if individual target items were successfully retrieved or suppressed. A logistic regression based on classifier output determined that retrieval activation during the cued recall/suppression period was a predictor for subsequent memory. Labeling trials with this internal measure, as opposed to their nominal Think vs. No-Think condition, revealed the classic TNT pattern of enhanced memory for successful cued-retrieval and degraded memory for cued-suppression. This classification process enabled a more selective investigation into the time-frequency signatures of control over retrieval. Comparing controlled retrieval vs. controlled suppression, results showed more prominent Theta oscillations (3 to 8 Hz) in controlled retrieval. Beta oscillations (12 to 30 Hz) were involved in high levels of both controlled retrieval and suppression, suggesting it may have a more general control-related role. These results suggest unique roles for these frequency bands in retrieval processes.