The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.
The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.
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DOI：
10.1111/bph.12449
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发表时间：
2013-12
影响因子：
7.3
通讯作者：
CGTP Collaborators
中科院分区：
文献类型：
--
作者：
Alexander SP;Benson HE;Faccenda E;Pawson AJ;Sharman JL;Spedding M;Peters JA;Harmar AJ;CGTP Collaborators
《2013/14年度药理学简明指南》简要概述了2000多种人类药物靶标的关键性质及其药理作用，并提供了药物靶标及其配体的开放获取知识库(www.guidetopPharmacology.org)的链接，其中提供了有关靶标和配体性质的更详细的视图。全文可在http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full.上找到。催化受体是该指南划分的七个主要药理靶点之一，其他是G蛋白偶联受体、配体门控离子通道、离子通道、核激素受体、转运体和酶。这些都提出了命名指南和最佳可用的药理学工具的摘要信息，以及关键参考资料和建议，以供进一步阅读。一种新的景观格式有易于使用的比较相关目标的表格。它是截至2013年底的当代材料的浓缩版本，在www.guidetopharmiacology.org网站上提供了更详细的内容并不断更新，取代了以前的受体和通道指南中提供的数据。它是与NC-IUPHAR联合编制的，并酌情提供了IUPHAR对人类药物靶标的正式分类和命名。它整合了以前在IUPHAR-DB和接收器和通道指南中单独管理和显示的信息，提供了一个永久的、可引用的时间点记录，该记录将在数据库更新后继续存在。
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. Catalytic receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates.
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影响因子：
3.6
作者：
Byfield, SD;Major, C;Roberts, AB
通讯作者：
Roberts, AB
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作者：
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通讯作者：
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