An efficient one-pot synthesis of dihydropyrimidinones catalyzed by zirconium hydrogen phosphate under solvent-free conditions

An efficient one-pot synthesis of dihydropyrimidinones catalyzed by zirconium hydrogen phosphate under solvent-free conditions
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DOI:
10.3906/kim-0912-357
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发表时间:
2010-01-01
影响因子:
1.4
通讯作者:
Nebioglu, Mehmet
Nebioglu, Mehmet
中科院分区:
化学4区
文献类型:
--
作者:
Besoluk, Senol;Kucukislamoglu, Mustafa;Nebioglu, Mehmet

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在无溶剂条件下,以磷酸氢锆[Zr(H2PO4)(2)]为新型固体酸催化剂,进行了一种简单、高效、实用的Biginelli反应。该催化剂具有良好的反应活性,可重复使用。
A simple, efficient, and practical procedure for the Biginelli reaction using zirconium hydrogen phosphate [Zr(H2PO4)(2)] as a novel solid acid catalyst is described under solvent-free conditions in high yields. The catalyst exhibited remarkable reactivity and it is reusable.