Cross-coupling of vinylpolysiloxanes with aryl iodides
Cross-coupling of vinylpolysiloxanes with aryl iodides
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DOI：
10.1016/s0022-328x(00)00894-9
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发表时间：
2001-04-01
影响因子：
2.3
通讯作者：
Wang, ZG
中科院分区：
文献类型：
--
作者：
Denmark, SE;Wang, ZG
在四丁基氟化铵（2 - 3当量）和Pd（dba）（2）（1-5摩尔%）的存在下，在室温下，市售的乙烯基聚硅氧烷（1）与芳基和烯基碘迅速进行交叉偶联反应，以高产率得到偶联产物。该方法采用廉价无毒的硅氧烷试剂，并显示出良好的官能团相容性和高立体定向性。(C)2001 Elsevier Science B. V.保留所有权利。
Commercially available vinylpolysiloxane (1) rapidly undergoes cross-coupling reactions with aryl and alkenyl iodides in the presence of tetrabutylammonium fluoride (two to three equivalents) and Pd(dba)(2) (1-5 mol%) at room temperature to afford coupling products in high yield. This process employs an inexpensive and non-toxic siloxane reagent and shows good functional group compatibility and high stereospecificity. (C) 2001 Elsevier Science B.V. All rights reserved.