Soft cluster-induced desorption and ionization of biomolecules-Influence of surface load and morphology on desorption efficiency
Soft cluster-induced desorption and ionization of biomolecules-Influence of surface load and morphology on desorption efficiency
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DOI：
10.1063/1.3664348
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发表时间：
2011-12-05
影响因子：
4
通讯作者：
Duerr, M.
中科院分区：
文献类型：
--
作者：
Baur, M.;Lee, B. -J.;Duerr, M.
中性团簇诱导的解吸和电离的寡肽都从μ m厚的膜，以及从表面制备的亚单层表面浓度的生物分子通过质谱仪进行了研究。从厚膜观察到最高信号强度，表明从块状材料的有效解吸。在亚单层制度，解吸的生物分子的离子信号被发现依赖于非线性的湿化学应用的生物分子的物质的量;观察相关的表面上的生物分子的聚集体的形成。(C)2011年美国物理学会。[doi：10.1063/1.3664348]
Neutral cluster-induced desorption and ionization of oligopeptides both from mu m-thick films as well as from surfaces prepared with submonolayer surface concentration of biomolecules was investigated by means of mass spectrometry. Highest signal intensity was observed from thick films indicating efficient desorption from bulk-like material. In the submonolayer regime, the ion signal of the desorbed biomolecules was found to depend nonlinearly on the amount of substance of the wet-chemically applied biomolecules; the observation is correlated to the formation of aggregates of biomolecules on the surface. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3664348]