Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation
Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation
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DOI：
10.1039/b822420j
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发表时间：
2009-01-01
影响因子：
4.9
通讯作者：
Sun, Xue-Long
中科院分区：
文献类型：
--
作者：
Zhang, Hailong;Ma, Yong;Sun, Xue-Long
基于Staudinger连接，在PBS缓冲液(pH 7.4)中，将带有叠氮间隔基的碳水化合物衍生物偶联到含有末端三膦的预制脂质体表面，建立了一种有效的、化学选择性的脂质体表面糖官能化方法。
An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBS buffer (pH 7.4) at room temperature.