First Report on a Hyperepidemic Clone of KPC-3-Producing Klebsiella pneumoniae in Israel Genetically Related to a Strain Causing Outbreaks in the United States

First Report on a Hyperepidemic Clone of KPC-3-Producing Klebsiella pneumoniae in Israel Genetically Related to a Strain Causing Outbreaks in the United States
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DOI:
10.1128/aac.00987-08
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发表时间:
2009-02-01
影响因子:
4.9
通讯作者:
Carmeli, Yehuda
Carmeli, Yehuda
中科院分区:
医学2区
文献类型:
--
作者:
Navon-Venezia, Shiri;Leavitt, Azita;Carmeli, Yehuda

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2006年,以色列出现了一种产生kpc -3的碳青霉烯耐药克隆肺炎克雷伯菌,引起了全国范围的暴发。该克隆在遗传上与2000年从美国分离的爆发菌株相关,但在携带kpc的质粒上有所不同。应认识并应对高流行性、广泛耐药菌株在全球蔓延的威胁。
A highly epidemic carbapenem-resistant clone of KPC-3-producing Klebsiella pneumoniae emerged in Israel in 2006, causing a nationwide outbreak. This clone was genetically related to outbreak strains from the United States isolated in 2000 but differed in KPC-carrying plasmids. The threat of the global spread of hyperepidemic, extensively drug-resistant bacterial strains should be recognized and confronted.