Hallucinations in adolescents and risk for mental disorders and suicidal behaviour in adulthood: Prospective evidence from the MUSP birth cohort study
Hallucinations in adolescents and risk for mental disorders and suicidal behaviour in adulthood: Prospective evidence from the MUSP birth cohort study
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DOI：
10.1016/j.schres.2016.06.009
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发表时间：
2016-10-01
影响因子：
4.5
通讯作者：
Scott, James G.
中科院分区：
文献类型：
--
作者：
Connell, Melissa;Betts, Kim;Scott, James G.
背景：幻觉，曾经被等同于严重的精神障碍，在青少年中很常见。鉴于幻觉的高流行率，重要的是确定它们是否与成年后的不利心理健康结果有关。本研究比较了(A)14岁、(B)14岁和21岁出现幻觉的受试者(年龄30-33岁)和无幻觉的受试者(年龄30-33岁)的心理健康结果。方法：受试者(n=333)年龄在30-33岁之间，(A)在14岁时在青年自我报告问卷上报告幻觉，在21岁时报告幻觉；(B)对照组(n=321)没有报告幻觉。终生精神障碍的诊断是通过临床心理学家实施的结构化DSM障碍临床访谈(DSM IV-TR)来确定的。自杀行为通过自我报告来衡量。结果：只有14岁的幻觉与成年后精神障碍的风险增加无关。14岁和21岁时报告的幻觉与终生诊断为精神障碍(OR，8.84；95%CI：1.61-48.43)和药物使用障碍(OR，2.34；95%CI：1.36-4.07)有关，也与终生自杀未遂(OR，7.11；95%CI：2.68-18.83)密切相关。结论：大多数出现幻觉的青少年成年后精神障碍的发生率没有增加；然而，那些在不止一个时间点经历幻觉的人，自杀行为以及精神病和非精神病精神病的风险都会增加。(C)2016爱思唯尔B.V.保留所有权利。
Background: Hallucinations, once equated with serious mental disorders, are common in adolescents. Given the high prevalence of hallucinations, it is important to determine if they are associated with adverse mental health outcomes in adulthood. This study compared the mental health outcomes of participants (aged 30-33 years) in the Mater-University of Queensland Study of Pregnancy (MUSP) who reported hallucinations at (a) 14 years only and (b) 14 and 21 years versus cohort members without hallucinations.Method: Participants (n = 333) were aged between 30 and 33 years and (a) reported hallucinations on the Youth Self-Report Questionnaire at 14 and/or the Young Adult Self-Report Questionnaire at 21 years and (b) controls (n = 321) who did not report hallucinations. Lifetime diagnoses of mental disorders were ascertained by the Structured Clinical Interview for DSM Disorders (DSM IV-TR) administered by clinical psychologists. Suicidal behaviour was measured by self report.Results: Hallucinations at 14 years only were not associated with an increased risk of mental disorders in adulthood. Hallucinations reported at both 14 and 21 years were associated with lifetime diagnoses of psychotic disorders (OR, 8.84; 95% CI: 1.61-48.43 and substance use disorders (OR, 2.34; 95% CI: 1.36-4.07) and also strongly associated with lifetime suicide attempts (OR, 7.11; 95% CI: 2.68-18.83).Conclusions: Most adolescents who experience hallucinations do not have an increased rate of mental disorder in adulthood; however, those with hallucinations that are experienced at more than one point in time are at increased risk of suicidal behaviour and both psychotic and non-psychotic psychopathology. (C) 2016 Elsevier B.V. All rights reserved.