When should clinicians switch treatments? An application of signal detection theory to two treatments for women with alcohol use disorders.
When should clinicians switch treatments? An application of signal detection theory to two treatments for women with alcohol use disorders.
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DOI：
10.1016/j.brat.2010.03.001
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发表时间：
2010-06
影响因子：
4.1
通讯作者：
Jensen N
中科院分区：
文献类型：
--
作者：
Hildebrandt T;McCrady B;Epstein E;Cook S;Jensen N
信号检测理论的统计学应用已被用于研究早期治疗反应在一系列治疗和精神疾病中的临床效用。本研究旨在通过对102名酒精使用障碍（AUDs）女性患者随机分为酒精行为个体治疗组（ABIT; n = 52）和酒精行为夫妇治疗组（ABCT; n = 50），采用受试者操作曲线（ROC）和零膨胀泊松（ZIP）回归分析，探讨每周治疗期间饮酒的预测价值。ROC分析表明，未能达到或维持禁欲结束的治疗和一年的后续预测与合理的准确性，由周-4%的禁欲（PDA）在ABIT。ZIP模型产生了类似的结果，有证据表明治疗内PDA与第6周PDA预测了治疗结束时和一年随访时的戒酒率以及饮酒天数百分比。尽管ABCT的总体治疗反应更好，但治疗内PDA是ABIT结局的明显更好的预测因素。逐步护理模式的酒精治疗的影响进行了讨论，并为今后的研究提出了建议。
Statistical application of signal detection theory has been used to study the clinical utility of early treatment response in a range of treatments and psychiatric disorders. The current study sought to examine the predictive value of weekly within-treatment drinking using receiver operator curves (ROCs) and zero-inflated Poisson (ZIP) regression in102 women with alcohol use disorders (AUDs) randomized to either alcohol behavioral individual treatment (ABIT; n = 52) or alcohol behavioral couples treatment (ABCT; n = 50). ROC analyses indicated that failure to achieve or sustain abstinence by the end-of-treatment and one year follow-up was predicted with reasonable accuracy by week-4 percent days abstinent (PDA) in ABIT. ZIP models yielded similar results with evidence for within treatment PDA with week-6 PDA predicting both the abstinence as well as percent days drinking at the end-of-treatment and one year follow-up. Within-treatment PDA was a significantly better predictor of outcomes for ABIT than ABCT, despite a better overall treatment response for ABCT. Implications for stepped care models of alcohol treatment are discussed and recommendations for future research made.
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影响因子：
17.7
作者：
Agras, WS;Crow, SJ;Kraemer, HC
通讯作者：
Kraemer, HC
影响因子：
5.9
作者：
Fals-Stewart, William;Birchler, Gary R.;Kelley, Michelle L.
通讯作者：
Kelley, Michelle L.
影响因子：
17.7
作者：
Fairburn, CG;Agras, WS;Stice, E
通讯作者：
Stice, E
影响因子：
4.6
作者：
Grove, WM;Lloyd, M
通讯作者：
Lloyd, M
DOI：
10.1111/j.1360-0443.2009.02611.x
发表时间：
2009-08
期刊：
Addiction (Abingdon, England)
影响因子：
--
作者：
Hunter-Reel D;McCrady B;Hildebrandt T
通讯作者：
Hildebrandt T