DEFECTS OF THE CENTRAL NERVOUS-SYSTEM IN FINLAND .4. ASSOCIATIONS WITH DIAGNOSTIC X-RAY EXAMINATIONS
DEFECTS OF THE CENTRAL NERVOUS-SYSTEM IN FINLAND .4. ASSOCIATIONS WITH DIAGNOSTIC X-RAY EXAMINATIONS
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DOI：
10.1016/0002-9378(79)90474-5
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发表时间：
1979-01-01
影响因子：
9.8
通讯作者：
GRANROTH, G
中科院分区：
文献类型：
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作者：
GRANROTH, G
根据芬兰先天性畸形登记册，进行了一项检索，以发现中枢神经系统缺陷与母亲怀孕期间的诊断性X射线检查以及怀孕前的盆腔X射线检查之间可能存在的关联。时间-地区匹配的怀孕和多指儿童作为对照。母亲在怀孕前做过骨盆X光检查的孩子患小头症的风险增加，但不一致的对的数量很少。在怀孕期间进行的检查中，胎儿X射线在分娩CNS缺陷儿童的母亲中显着更常见。其他类型的考试没有观察到相关性。
Based on the Finnish Register of Congenital Malformations a search was undertaken to find possible associations between defects of the CNS and diagnostic X-ray examinations of the mother during pregnancy, as well as pelvic X-ray examinations prior to pregnancy. Time-area-matched pregnancies and polydactylic children were used as controls. The risk of having a microcephalic child was increased for mothers with pelvic X-ray prior to pregnancy but the number of discordant pairs was small. Of the examinations performed during pregnancy, fetal X-ray was significantly more common among mothers who delivered a CNS-defective child. No associations were observed for other kinds of examinations.