Magnetic resonance imaging features of ovarian fibroma, fibrothecoma, and thecoma
Magnetic resonance imaging features of ovarian fibroma, fibrothecoma, and thecoma
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DOI：
10.1007/s00261-014-0257-z
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发表时间：
2015-06-01
影响因子：
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通讯作者：
Oh, Yoon Jin
中科院分区：
文献类型：
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作者：
Chung, Bo Mi;Park, Sung Bin;Oh, Yoon Jin
为探讨卵巢纤维瘤、纤维瘤和卵泡膜瘤的常规和功能性(弥散或灌注加权)磁共振成像特征，对26例经组织学证实的卵巢纤维瘤(n=19)、纤维鞘瘤(n=7)和卵泡膜瘤(n=2)进行了分析。分析28例常规MRI的形态和信号强度(SI)特征。分析弥散加权像(DWI)b(1000)信号强度(n=22)和灌注加权像(PWI)b(1000)信号强度曲线(n=7)。T2加权像评估病变周围同侧卵巢组织的存在和形态。22例(79%)以实体瘤为主。大多数病灶在T1加权像(24/28，86%)和T2加权像(19/28，68%)上表现为均匀的低信号。相反，一些病灶在T2加权像上表现为高信号(9/28，32%)。大多数病灶在T2加权像上可检出同侧卵巢(24/28，86%)。大于6 cm的肿瘤更可能表现为不典型的形态(实性和囊性混合，囊性)，不典型的SI(T1和T2加权像高)和大量腹水。较大的肿瘤组(>；6厘米)更有可能被病理诊断为纤维瘤或卵泡膜瘤而不是纤维瘤。在DWI上，16个病灶呈低b(1000)信号(16/22，73%)。在PWI上，所有病变均呈曲线型1或2(7/7,100%)，倾向于良性病变。所有绝经前妇女(16/16,100%)均有同侧卵巢可检出，10名绝经后妇女中有6人(60%)有同侧卵巢可检出(P<；0.05)。结合常规的形态和信号强度特征与DWI或PWI的结果相结合，可能有助于卵巢纤维瘤、纤维瘤和卵巢癌与卵巢恶性肿瘤的鉴别，尽管还需要进一步的更大规模的DWI和PWI研究。
To retrospectively evaluate the conventional and functional (diffusion- or perfusion-weighted) magnetic resonance (MR) imaging features of ovarian fibroma, fibrothecoma, and thecoma.Histologically proven ovarian fibromas (n = 19), fibrothecomas (n = 7), and thecomas (n = 2) were reviewed (26 patients). The morphologic and signal intensity (SI) characteristics on conventional MR imaging (n = 28, all cases) were analyzed. The b (1000) signal intensity on diffusion-weighted image (DWI) (n = 22) and the time-to-signal intensity curve on perfusion-weighted image (PWI) (n = 7) were also analyzed. The presence and shape of the ipsilateral ovarian tissue surrounding the lesions were evaluated on T2-weighted image.Twenty-two cases (79%) were predominantly solid tumor. Majority of the detected lesions exhibited the characteristic homogeneous low SI on T1- (24/28, 86%) and T2- (19/28, 68%) weighted image. Conversely, a number of lesions exhibited high SI (9/28, 32%) on T2-weighted image. Most lesions presented with a detectable ipsilateral ovary on T2-weighted image (24/28, 86%). Tumors larger than 6 cm more likely showed atypical morphology (mixed solid and cystic, cystic), atypical SI (high on T1- and T2-weighted image), and large amount ascites. Larger tumor group (> 6 cm) was more likely diagnosed as fibrothecoma or thecoma than fibroma by pathology. On DWI, 16 lesions showed low b (1000) signal intensity (16/22, 73%). On PWI, all lesions showed curve type 1 or 2 (7/7, 100%), which tends to characterize benign lesions. All (16/16, 100%) pre-menopausal women had a detectable ipsilateral ovary, and six (60%) out of 10 post-menopausal women had a detectable ipsilateral ovary (p < 0.05).Combining conventional morphologic and signal intensity characteristics with the findings from DWI or PWI might help differentiate ovarian fibroma, fibrothecoma, and thecoma from ovarian malignancy, although further prospective larger scale study using DWI and PWI is needed.