Long-alkane-chain modified N-phthaloyl chitosan membranes with controlled permeability
Long-alkane-chain modified N-phthaloyl chitosan membranes with controlled permeability
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DOI：
10.1016/j.carbpol.2012.08.042
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发表时间：
2013-01-02
影响因子：
11.2
通讯作者：
Hu, Shuwen
中科院分区：
文献类型：
--
作者：
Chen, Chao;Tao, Shuming;Hu, Shuwen
通过对壳聚糖氨基的区域选择性保护，得到相应的邻苯二甲酰亚胺，再与长链十二酰氯反应，合成了一系列具有可控渗透性的N-邻苯二甲酰化壳聚糖膜。傅里叶变换红外光谱（FT-IR）和H-1核磁共振（H-1 NMR）分析表明，取代度（DS）范围为2.8至3.6。接触角、保水值和力学性能测试表明，改性后膜的疏水性和力学性能均得到显著改善，同时膜在多种有机溶剂中的溶解性也得到提高。热重量变化分析表明，较高的DS提供增强的热性能。通过测量尿素的扩散来确定膜的受控渗透性，并且随着DS的增加，释放的尿素量显着减少。膜的综合性能可以通过调节DS值来调节。(C)2012爱思唯尔有限公司保留所有权利。
A series of N-phthaloyl acylated chitosan membranes with controlled permeability were synthesized by the regioselective protection of the chitosan amino groups as the corresponding phthalimides followed by reaction with the long-chain dodecanoyl chloride. Fourier transform infrared (FT-IR) and H-1 nuclear magnetic resonance (H-1 NMR) analysis suggested that the degree of substitution (DS) ranged from 2.8 to 3.6. Contact angles, water retention values and mechanical examinations demonstrated that the hydrophobicity and mechanical properties of the membranes were all improved significantly following the modifications, together with their solubility in many organic solvents. Thermal weight change analysis demonstrated that a higher DS provided enhanced thermal properties. The controlled permeability of the membranes was determined by measuring the diffusion of urea, and the amount of urea released decreased significantly with increasing DS. The comprehensive properties of the membranes could be tuned by regulating their DS values as required. (C) 2012 Elsevier Ltd. All rights reserved.