Leukocyte and fibroblast interferon genes are located on human chromosome 9.
Leukocyte and fibroblast interferon genes are located on human chromosome 9.
复制标题
白细胞和成纤维细胞干扰素基因位于人类第9号染色体上。
DOI：
10.1073/pnas.78.5.3123
复制
发表时间：
1981
影响因子：
11.1
通讯作者：
Lawn,RM
中科院分区：
文献类型：
--
作者：
Owerbach,D;Rutter,WJ;Shows,TB;Gray,P;Goeddel,DV;Lawn,RM
人类9号染色体上至少有8个白细胞干扰素基因(IFL)和单个成纤维细胞干扰素基因(IFF)。在人类和小鼠细胞的体细胞杂交中，含有正常的小鼠亲本细胞染色体，但人类染色体的数量减少，只有当人类9号染色体也存在时，才会出现人白细胞和成纤维细胞干扰素DNA序列。
At least eight leukocyte interferon genes (IFL) and the single fibroblast interferon gene (IFF) have been located on chromosome 9 in humans. In somatic cell hybrids of human and mouse cells containing a normal complement of mouse parental cell chromosomes but reduced numbers of human chromosomes, the human leukocyte and fibroblast interferon DNA sequences were present only when human chromosome 9 was also present.