Three-dimensional microtomographic imaging of human brain cortex
Three-dimensional microtomographic imaging of human brain cortex
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DOI：
10.1016/j.brainres.2008.01.029
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发表时间：
2008-03-14
期刊：
影响因子：
2.9
通讯作者：
Suzuki, Yoshio
中科院分区：
文献类型：
--
作者：
Mizutani, Ryuta;Takeuchi, Akihisa;Suzuki, Yoshio
本文描述了一种用于成像人脑皮质三维结构的X射线显微层析成像技术。大脑中的神经元构成了一个三维网络的神经回路。脑组织是由光元素组成的，在硬X射线传输图像中对比度很小。用金属化合物对神经细胞进行染色，增强了对比度。获得的结构揭示了额叶皮质灰质区和白质区的微结构，这与较高的大脑功能有关。
This paperdescribes an X-ray microtomographic technique for imaging the three-dimensional structure of the human cerebral cortex. Neurons in the brain constitute a neural circuit as a three-dimensional network. The brain tissue is composed of light elements that give little contrast in a hard X-ray transmission image. The contrast was enhanced by staining neural cells with metal compounds. The obtained structure revealed the microarchitecture of the gray and white matter regions of the frontal cortex, which is responsible for the higher brain functions.