Does Retinotopy Influence Cortical Folding in Primate Visual Cortex?
Does Retinotopy Influence Cortical Folding in Primate Visual Cortex?
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DOI：
10.1523/jneurosci.1835-09.2009
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发表时间：
2009-09-09
影响因子：
5.3
通讯作者：
Tootell, Roger B. H.
中科院分区：
文献类型：
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作者：
Rajimehr, Reza;Tootell, Roger B. H.
在人类和其他东半球灵长类动物中，大部分视觉皮层由一组视网膜定位图组成，嵌入皮层薄片中，具有众所周知的可识别的折叠模式。然而，这两个突出的皮质变量之间的关系尚未得到全面的研究。在这里，我们用猴子和人类的功能和结构磁共振成像定量地测试了这种关系。我们发现，视野的垂直子午线倾向于在脑回（凸褶）上表现，而水平子午线倾向于在沟（凹褶）上表现，贯穿两种灵长类动物的视觉皮层。这种关系表明，视网膜定位图可能限制了发育过程中皮质折叠的模式。
In humans and other Old World primates, much of visual cortex comprises a set of retinotopic maps, embedded in a cortical sheet with well known, identifiable folding patterns. However, the relationship between these two prominent cortical variables has not been comprehensively studied. Here, we quantitatively tested this relationship using functional and structural magnetic resonance imaging in monkeys and humans. We found that the vertical meridian of the visual field tends to be represented on gyri (convex folds), whereas the horizontal meridian is preferentially represented in sulci (concave folds), throughout visual cortex in both primate species. This relationship suggests that the retinotopic maps may constrain the pattern of cortical folding during development.